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Enjoy sleeping fast and without waking up thanks to our melatonin and tryptophan formula. Not only improve sleep quality and mood, but also boost your immune system.
Enjoy sleeping fast and without waking up thanks to our melatonin and tryptophan formula. Not only improve sleep quality and mood, but also boost your immune system.
What is it?
Melatonin is an endogenous hormone and released exclusively at night. Its biosynthesis depends on the availability of L-tryptophan (Trp), an essential amino acid in humans and precursor of serotonin. Melatonin is centrally involved in circadian rhythmicity maintenance and sleep regulation, and acts as an antioxidant and immunostimulant agent.
Where can I find them?
Melatonin is endogenous produced by pineal gland in the human body. However, its synthesis depends on L-tryptophan, which your body cannot produce, so you must get it from your diet, like eggs, milk, soy, banana, nuts, fatty fish, meat, whole grains, etc.
Why do I need it?
With aging, melatonin production drops and troubles to fall and/or stay asleep appear, getting worse quality of life. Moreover, it is an alternative to commonly used sedative drugs, avoiding dependency and addiction.
Kobho's melatonin formula helps to stimulate sleep but also to maintain its quality throughout the night.
Melatonin is the only hormone that has a potent antioxidant activity, surpassing the effects of vitamins C and E.
During night sleep, the immune system neutralizes free radicals, strengthens memory and rebuilds body tissues.
Source: Razali, S. et al. (2020) “Design of multi-particulate ‘Dome matrix’ with sustained-release melatonin and delayed-release caffeine for jet lag treatment,” International journal of pharmaceutics, 587(119618), p. 119618.
Kobho’s sleep formula is composed of 8 synergic ingredients through two layers. At first, melatonin is released, and its hypnotic effect promotes sleep onset and continuity, followed by a progressive release of the rest of the ingredients that maintain it throughout the night. Most alternatives just release melatonin at the beginning and consequently cause nocturnal awakenings.
Sleep onset latency is reduced by hypnotic and inductive effect of melatonin. So you will notice an increase in your hours of sleep that will make you feel better and more awake during the day.
The production of melatonin begins to be regulated in your body and the biological rhythms are adjusted for its secretion at night. In addition, our formula increases serotonin production that will help you to improve your mood.
You will notice how your body is immersed in total relaxation and your level of mental and physical stress decreases. In addition, it improves immune response and mental performance.
The action of the different ingredients in sleep regulation, and improvement of physical and mental performance and immune response will help you to wake up feeling rested and perform well during the day.
Nucleotides, GABA and other ingredients act synergistically to regulate sleep through diverse mechanisms, and to improve immune response.
Our bilayer tablets allow a release of the ingredients throughout the night to maintain sleep.
Melatonin is a hormone produced by the brain in response to darkness. It helps control circadian rhythms. It is involved in sleep quality. Its main function is to alert organs to light and dark cycles, in order to carry out their functions.
L-Tryptophan is an essential amino acid that acts as a precursor of serotonin and melatonin. It participates in sleep regulation and sleep latency. It increases the bioavailability of serotonin in the brain, and together, they have direct effects on sleep and mood improvement.
Gamma-amino-butyric acid (GABA) is an amino acid that works as the primary inhibitory neurotransmitter for the central nervous system. It reduces neuronal excitability by inhibiting nerve transmission, so it promotes sleep. In addition, together with L-Theanine, it decreases sleep latency and increases sleep duration improving REM sleep.
Nucleotides are semi-essential nutrients that play a wide variety of roles in cellular metabolism, which translates into good gut and immune response. They play a key role in cognitive function by enhancing memory and learning through regulation of REM sleep. In addition, uridine mediates sleep induction through its receptor in the central nervous system.
It is an essential micronutrient for humans and is found in several foods, such as meat, fish, legumes and nuts. Zinc is involved in different metabolic processes and immune function.
Vitamin B6 or pyridoxine is an essential water-soluble vitamin. It is involved in energy metabolism and protein synthesis. It also supports nervous system functions. It provides synergistic benefits with magnesium and melatonin, helping to reduce fatigue and regulate sleep.
It is an amino acid that acts with GABA increasing the quality and time of sleep. It also decreases stress-related symptoms and improves cognitive function.
Bulking agent (microcrystalline cellulose), L-tryptophan, shade green-powder (EXBERRY) (spirulina and safflower concentrate), gamma-aminobutyric acid, glazing agent (hydroxypropyl methylcellulose), bulking agent (calcium phosphates), green tea extract (Camellia sinensis, leaves) 60% L-theanine, 0,38 epigallocatechin gallate (EGCG), zinc oxide, nucleotide uridine 5-monophosphate (uridine), nucleotide cytidine 5-monophosphate (cytidine), anti-caking agents (magnesium salts of fatty acids and silicon dioxide), melatonin, pyridoxine hydrochioride (vitamin B6).
Allergen Free
Food supplements should not be used as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the stated recommended daily dose. Keep out of reach of young children. Not to be consumed if other products containing green tea are already consumed in the same day. Not for use by pregnant or breastfeeding women, or by patients under 18 years of age. It should not be taken in an empty stomach. It should not be consumed by pregnant women, or by those being treated with anti-depressants or suffering from renal insufficiency. Do not use it for prolonged periods without medical advice. Store in a cool dry place.
Net quantity: 36.0g
Distributed by: Evolvere Science Labs S.L.
Calle de Zurbano, 23, 28010 Madrid, España.
At the age of 30, the synthesis of melatonin begins to drop, so your sleep quality gets worse. If you notice trouble falling and/or staying asleep, wake up tired or suffer from jet lag, it is possible that your melatonin production is altered and you need a supplement.
Melatonin can be safely consumed for periods of 6 months with breaks between them. We recommend taking advantage of the summer to rest, as it usually improves melatonin synthesis. However, in case of severe sleep problems, we recommend seeing a doctor.
We have been working on a formulation that not only improves sleep quality, but also boosts mood and contributes to a health immune system.
Sleep deprivation impairs learning and memory, causes moodiness and fatigue, and weakens immune system. This lack of sleep can be caused by age, medical conditions and external factors, such as work, stress, poor sleep hygiene, lifestyle, etc.
Llevo semanas tomándola y duermo mucho mejor sobre todo no me despierto por las noches.